Light Microscopy

Core Mission Statement

The mission of this facility is to provide state of the art equipment, training, and image processing capabilities to assist researchers within the NHLBI-DIR in experiments involving light microscopy. Equipment within the facility includes several types of confocal microscopes, a two-photon microscope, and standard epi-fluorescence wide-field microscopes. This range of instruments provides capabilities for live cell imaging, deep tissue-level imaging, video-rate confocal imaging, spectral imaging, and simple wide-field fluorescence and bright-field imaging of prepared slides.  We also have a suite of image processing capabilities that includes basic image analysis as well as FRAP analysis, colocalization analysis, deconvolution, particle tracking, and 3D reconstruction as well as a custom in-house image processing programs for specific applications.

Lab Employees

Christian Combs, Ph.D. | Director

combsc@nhlbi.nih.gov

 

Daniela Malide, Ph.D., M.D. | Bldg. 10 Site Facility Manager

dmalide@nih.gov

 

Xufeng Wu, Ph.D. |  Deputy Director

wux@nhlbi.nih.gov

 

Location

Dr.'s Combs and Malide Location                         Dr. Wu's Location
National Heart, Lung, and Blood Institute
Building 10, Room 6N-309
10 Center Drive MSC 1623
Bethesda, MD 20892
National Heart, Lung, and Blood Institute
Building 50, Room 2318
10 Center Drive MSC 1623
Bethesda, MD 20892

Links and Resources

  1. NHI Heart, Lung and Blood Institute Web site: http://www.nhlbi.nih.gov/